Acta Biochimica et Biophysica Sinica

Editorial

• New hopes in the fight against cancer: a special issue on targeted anti-cancer drug discovery and cell signaling

  Xiaodong Cheng

  Acta Biochim Biophys Sin 2016, 48: 1�C2; doi: 10.1093/abbs/gmv117

  [Abstract]  [PDF]  [Full Text]

Reviews

• Computational allosteric ligand binding site identification on Ras proteins

  Michael McCarthy,

  Priyanka Prakash and

  Alemayehu A. Gorfe

  Acta Biochim Biophys Sin 2016, 48: 3�C10; doi: 10.1093/abbs/gmv100

  [Abstract]  [PDF]  [Full Text]

• Targeting KRAS-mutant non-small cell lung cancer: challenges and opportunities

  Jun Zhang,

  Dongkyoo Park,

  Dong M. Shin and

  Xingming Deng

  Acta Biochim Biophys Sin 2016, 48: 11�C16; doi: 10.1093/abbs/gmv118

  [Abstract]  [PDF]  [Full Text]

• The greedy nature of mutant RAS: a boon for drug discovery targeting cancer metabolism?

  Jing Lv,

  Jieqiong Wang,

  Siyu Chang,

  Mingyao Liu and

  Xiufeng Pang

  Acta Biochim Biophys Sin 2016, 48: 17�C26; doi: 10.1093/abbs/gmv102

  [Abstract]  [PDF]  [Full Text]

• RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies

  Bingliang Fang

  Acta Biochim Biophys Sin 2016, 48: 27�C38; doi: 10.1093/abbs/gmv090

  [Abstract]  [PDF]  [Full Text]

• HER3/ErbB3, an emerging cancer therapeutic target

  Ningyan Zhang,

  Yujun Chang,

  Adan Rios and

  Zhiqiang An

  Acta Biochim Biophys Sin 2016, 48: 39�C48; doi: 10.1093/abbs/gmv103

  [Abstract]  [PDF]  [Full Text]

• Targeting truncated RXRα for cancer therapy

  Xiaokun Zhang,

  Hu Zhou and

  Ying Su

  Acta Biochim Biophys Sin 2016, 48: 49�C59; doi: 10.1093/abbs/gmv104

  [Abstract]  [PDF]  [Full Text]

• Autophagy regulation in the development and treatment of breast cancer

  Yuting Zhou,

  Edmund B. Rucker III and

  Binhua P. Zhou

  Acta Biochim Biophys Sin 2016, 48: 60�C74; doi: 10.1093/abbs/gmv119

  [Abstract]  [PDF]  [Full Text]

• The pleiotropic role of exchange protein directly activated by cAMP 1 (EPAC1) in cancer: implications for therapeutic intervention

  Muayad Almahariq,

  Fang C. Mei and

  Xiaodong Cheng

  Acta Biochim Biophys Sin 2016, 48: 75�C81; doi: 10.1093/abbs/gmv115

  [Abstract]  [PDF]  [Full Text]

• Multifaceted roles for thymine DNA glycosylase in embryonic development and human carcinogenesis

  Xuehe Xu,

  David S. Watt and

  Chunming Liu

  Acta Biochim Biophys Sin 2016, 48: 82�C89; doi: 10.1093/abbs/gmv083

  [Abstract]  [PDF]  [Full Text]

• Identifying therapeutic targets in gastric cancer: the current status and future direction

  Beiqin Yu and

  Jingwu Xie

  Acta Biochim Biophys Sin 2016, 48: 90�C96; doi: 10.1093/abbs/gmv084

  [Abstract]  [PDF]  [Full Text]

• Targeting epigenetic regulations in cancer

  Bo Ning,

  Wenyuan Li,

  Wei Zhao and

  Rongfu Wang

  Acta Biochim Biophys Sin 2016, 48: 97�C109; doi: 10.1093/abbs/gmv116

  [Abstract]  [PDF]  [Full Text]